- 询价
- Miltenyi Biotec
- 德国
- 130-100-924
- 2025年12月09日
- Flow cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD85h (ILT1)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA219
- 标记物：
APC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:11
- 抗体英文名：
CD85h (ILT1) Antibody, anti-human, REAfinity™
- 抗体名：
CD85h (ILT1) Antibody, anti-human, REAfinity™
- 规格：
100 tests in 1 mL
Identification and enumeration of CD85h (ILT1)+ cells by flow cytometryClone REA219 recognizes CD85h (ILT1), a member of the immunoglobulin-like transcripts (ILT) family of proteins. ILT family members compose of both activating and inhibitory receptors, where CD85h serves as an activating receptor. In contrast to inhibitory members, CD85h posesses a positively charged amino acid in its trasmembrane domain and a short cytoplasmic domain which is devoid of sequence motifs involved in signal transduction. To transduce activating signal, ILT1 forms a multiprotein complex with FCεRIγ. Expression of ILT1 is found on the surface of monocytes/macrophages, dendritic cells, and on a small subset of NK cells. | Additional information: Clone REA219 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Nakajima, H. et al. (1999) Cutting edge: human myeloid cells express an activating ILT receptor (ILT1) that associates with Fc receptor γ-chain. J Immunol 162: 5–8. | Chen, Y. et al. (2009) Crystal structure of myeloid cell activating receptor leukocyte Ig-like receptor A2 (LILRA2/ILT1/LIR-7) domain swapped dimer: molecular basis for its non-binding to MHC complexes. J. Mol. Biol. 386 (3): 841–853.
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CD85h (ILT1) Antibody, anti-human, APC, REAfinity™, 100 tests in 1 mL
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