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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD8
- 亚型:
recombinant human IgG1
- 形态:
Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
- 保存条件:
避光,4-8℃
- 克隆性:
REA734
- 标记物:
pure
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi biotec
- 宿主:
human cell line
- 应用范围:
Mass cytometry, MICS (MACSima Imaging Cyclic Staining), 3D-Immunofluorescence, Immunofluorescence, Immunohistochemistry, Mass cytometry
- 抗体英文名:
CD8 Antibody, anti-human, REAfinity™
- 抗体名:
CD8 Antibody, anti-human, REAfinity™
- 规格:
100 µg in 100 µL
Identification and enumeration of CD8+ cells by mass cytometryClone REA734 recognizes the human CD8 antigen, a cell-surface glycoprotein also known as Leu-2 or CD8a. CD8 is strongly expressed on human cytotoxic T cells and thymocytes as well as on a subset of natural killer (NK) cells. The CD8 antigen is a disulfide-linked dimer that exists either as a CD8a homodimer or as a CD8α/β heterodimer. CD8 acts as a coreceptor for the T cell receptor and binds to the MHC class I molecules. CD8 is involved in T cell development and activation of mature T cells. The CD8 antibody recognizes the α-subunit of the antigen. | Additional information: Clone REA734 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Devine, L. et al. (1999) Orientation of the Ig domains of CD8 alpha beta relative to MHC class I. J Immunol 162 (2): 846–851. | Gao, G. F. et al. (2000) Molecular interactions of coreceptor CD8 and MHC class I: the molecular basis for functional coordination with the T-cell receptor. Immunol. Today 21 (12): 630–636.
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CD8 Antibody, anti-human, pure, REAfinity™, 100 µg in 100 µL
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