- 询价
- Miltenyi Biotec
- 德国
- 130-119-787
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Mass cytometry
- human cell line
- human, non-human primate
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD81
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA513
- 标记物：
APC
- 适应物种：
human, non-human primate
- 保质期：
24个月
- 供应商：
Miltenyi biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Mass cytometry
- 浓度：
1:50
- 抗体英文名：
CD81 Antibody, anti-human, REAfinity™
- 抗体名：
CD81 Antibody, anti-human, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of CD81+ cells by flow cytometryClone REA513 recognizes the human CD81 antigen, a multi-pass membrane protein also known as TAPA-1. It is a member of the tetraspanin family including, for example, CD9, CD37, CD53, CD63, CD82, and CD151. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth, and motility. The 26 kDa cell surface protein is involved in adhesion, activation, proliferation, and differentiation of B cells, T cells, and other cells. On B cells CD81 is part of a complex with CD21, CD19, and Leu13. Similarly on T cells CD81 associates with CD4 and CD8 and provides a costimulatory signal with CD3. CD81 is expressed by epithelial and endothelial cells, T and B cells, as well as natural killer (NK) cells. | Additional information: Clone REA513 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Levy, S. (1998) CD81 (TAPA-1): a molecule involved in signal transduction and cell adhesion in the immune system. Annu. Rev. Immunol. 16: 89–109. | Wright, M. D. et al. (1994) The ins and outs of the transmembrane 4 superfamily. Immunol. Today 15 (12): 588–594. | Levy, S. (1991) Structure and membrane topology of TAPA-1. J. Biol. Chem. 266 (22): 14597–14602. | Oren, R. (1990) TAPA-1, the target of an antiproliferative antibody, defines a new family of transmembrane proteins. Mol. Cell. Biol. 10 (8): 4007–4015.
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CD81 Antibody, anti-human, APC, REAfinity™, 100 tests in 200 µL
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