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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD68
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA835
- 标记物:
Biotin
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi biotec
- 宿主:
human cell line
- 应用范围:
Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), 3D-Immunofluorescence, Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
CD68 Antibody, anti-mouse, REAfinity™
- 抗体名:
CD68 Antibody, anti-mouse, REAfinity™
- 规格:
30 µg in 200 µL
Identification and enumeration of CD68+ cells by flow cytometryClone REA835 recognizes mouse CD68 antigen, also known as macrosialin, which is a heavily glycosylated type I transmembrane protein of the lysosomal-associated membrane protein (LAMP) family. It is expressed on tissue macrophages, Langerhans cells, and at a low density on dendritic cells. Murine CD68 is predominantly intracellular but it is reported that 10–15% of CD68 is expressed on the cell surface as well. Macrosialin functions as a macrophage receptor for oxidized low density lipoprotein. | Additional information: Clone REA835 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Smith, M. J. et al. (1987) Differential expression of murine macrophage surface glycoprotein antigens in intracellular membranes. J. Cell. Sci. 87: 113–119. | Ramprasad, M. P. et al. (1996) Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein. Proc. Natl. Acad. Sci. U.S.A. 93: 14833–14838. | Kurushima, H. et al. (2000) Surface expression and rapid internalization of macrosialin (mouse CD68) on elicited mouse peritoneal macrophages. J Leukoc Biol 67: 104–108.
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CD68 Antibody, anti-mouse, Biotin, REAfinity™, 30 µg in 200 µL
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