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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD66c
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA414
- 标记物:
Biotin
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
CD66c Antibody, anti-human, REAfinity™
- 抗体名:
CD66c Antibody, anti-human, REAfinity™
- 规格:
100 tests in 200 µL
Identification and enumeration of CD66c+ cells by flow cytometryClone REA414 recognizes the human CD66c antigen, a glycosylphosphatidylinositol (GPI) linked protein, which is also known as carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6). Within the hematopoietic system, CD66c expression is limited to granulocytes and its precursors, where it serves homotypic and heterotypic adhesion, Ca 2)+ mediated signaling, and is markedly upregulated from intracellular stores after activation. It is also found in epithelia of various organs. CD66c overexpression is found in a wide variety of epithelial cancer types such as lung, breast, colorectal, and hepatocellular carcinomas. | Additional information: Clone REA414 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Neumaier, M. et al. (1988) Characterization of a cDNA clone for the nonspecific cross-reacting antigen (NCA) and a comparison of NCA and carcinoembryonic antigen. J. Biol. Chem. 263 (7): 3202–3207. | Guillaume, N. et al. (2011) CD66c expression in B-cell acute lymphoblastic leukemia: strength and weakness. Int J Lab Hematol 33 (1): 92–96. | Kiyokawa, N. et al. (2014) Significance of CD66c expression in childhood acute lymphoblastic leukemia. Leuk. Res. 38 (1): 42–48.
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CD66c Antibody, anti-human, Biotin, REAfinity™, 100 tests in 200 µL
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