- 询价
- Miltenyi Biotec
- 德国
- 130-115-459
- 2025年12月09日
- Flow cytometry
- human cell line
- mouse
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD69
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA937
- 标记物：
FITC
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 抗体英文名：
CD69 Antibody, anti-mouse, REAfinity™
- 抗体名：
CD69 Antibody, anti-mouse, REAfinity™
- 规格：
150 µg in 1 mL
Identification and enumeration of CD69+ cells by flow cytometryClone REA937 recognizes the mouse CD69 antigen, a type II integral membrane protein with a C-type lectin domain. CD69 is expressed as a homodimer composed of heavily glycosylated subunits. It is rapidly induced upon activation of T and B cells, neutrophils, and NK cells, which is why CD69 has been mostly regarded as an activation marker. The precise role of CD69 in immunity has not been determined because its ligand is unknown. Freshly prepared thymocytes undergoing selection events express CD69, and regulatory roles for CD69 expression in T cell development in the thymus have been suggested. However, phenotypical analysis in previous studies using CD69-deficient mice has revealed that CD69 does not appear to be required for the development of CD4 T cells. CD69 is also expressed on platelets. Recent studies have shown that CD69 is constitutively expressed by tissue-resident Tʜ memory cells and that its function is essential for the generation of professional resting memory Tʜ cells. | Additional information: Clone REA937 displays negligible binding to Fc receptors.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验该产品被引用文献
Sancho, D. et al. (2005) CD69 is an immunoregulatory molecule induced following activation. Trends Immunol. 26 (3): 136–140. | Shinoda, K. et al. (2012) Type II membrane protein CD69 regulates the formation of resting T-helper memory. Proc. Natl. Acad. Sci. U.S.A. 109 (19): 7409–7414. | Sathaliyawala, T. et al. (2013) Distribution and compartmentalization of human circulating and tissue-resident memory T cell subsets. Immunity 38 (1): 187–197.
技术资料暂无技术资料 索取技术资料
文献支持
CD69 Antibody, anti-mouse, FITC, REAfinity™, 150 µg in 1 mL
询价
