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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD62L
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA828
- 标记物:
PE-Vio 615
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
CD62L Antibody, anti-mouse, REAfinity™
- 抗体名:
CD62L Antibody, anti-mouse, REAfinity™
- 规格:
30 µg in 200 µL
Identification and enumeration of CD62L+ cells by flow cytometryClone REA828 recognizes mouse CD62L, also known as L-selectin. CD62L is a member of the selectin family of cell adhesion molecules. CD62L is important for the homing of lymphocytes to peripheral lymph nodes through high endothelial venules. It also contributes to leukocyte emigration into acute inflammatory sites. CD62L is a glycoprotein expressed on the cell surface of most thymocytes, T cells, B cells, monocytes, dendritic cells, neutrophils, and eosinophils. It is highly expressed on naive T cells and down-regulated upon differentiation due to activation-dependent shedding. CD62L is also expressed on a subset of CCR7highCD44high central memory T cells and on CD4+CD25+ regulatory T cells. | Additional information: Clone REA828 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Siegelman, M. H. et al. (1990) The mouse lymph node homing receptor is identical with the lymphocyte cell surface marker Ly-22: role of the EGF domain in endothelial binding. Cell 61 (4): 611–622. | Gallatin, W. M. et al. (2006) A cell-surface molecule involved in organ-specific homing of lymphocytes. J Immunol 177 (1): 5–9.
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CD62L Antibody, anti-mouse, PE-Vio® 615, REAfinity™, 30 µg in 200 µL
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