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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD53
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA512
- 标记物:
Biotin
- 适应物种:
rat
- 保质期:
24个月
- 供应商:
Miltenyi biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:10
- 抗体英文名:
CD53 Antibody, anti-rat, REAfinity™
- 抗体名:
CD53 Antibody, anti-rat, REAfinity™
- 规格:
9 µg in 300 µL
Identification and enumeration of CD53+ cells by flow cytometryClone REA512 recognizes the rat CD53 antigen, also known as Ox-44, a 43 kDa glycoprotein and a member of the tetraspanin family, which has four transmembrane domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth, and motility. CD53 is expressed on almost all hematopoietic cells such as B cells, monocytes, macrophages, neutrophils, und T cells, but not on erythrocytes and platelets. | Additional information: Clone REA512 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Tomlinson, M. G. (1993) Epitope mapping of anti-rat CD53 monoclonal antibodies. Implications for the membrane orientation of the Transmembrane 4 Superfamily. Eur. J. Immunol. 23 (1): 136–140. | Lazo, P. A. et al. (1997) Ligation of CD53/OX44, a tetraspan antigen, induces homotypic adhesion mediated by specific cell-cell interactions. Cell. Immunol. 178 (2): 132–140. | Bellacosa, A. (1991) The rat leukocyte antigen MRC OX-44 is a member of a new family of cell surface proteins which appear to be involved in growth regulation. Mol. Cell. Biol. 11 (5): 2864–2872.
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CD53 Antibody, anti-rat, Biotin, REAfinity™, 9 µg in 300 µL
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