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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD5
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA421
- 标记物:
APC-Vio 770
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
CD5 Antibody, anti-mouse, REAfinity™
- 抗体名:
CD5 Antibody, anti-mouse, REAfinity™
- 规格:
30 µg in 200 µL
Identification and enumeration of CD5+ cells by flow cytometryClone REA421 recognizes the mouse CD5 antigen, a 67 kDa single-pass type I membrane protein which is also known as lymphocyte antigen 1 (Ly-1). CD5 is expressed by a majority of thymocytes, mature T cells, and a subset of B cells. The expression of CD5 by a small B cell subset characterizes a developmentally and functionally distinct lineage of B cells called B-1a cells. CD5 plays a role in the interaction of T and B cells and is a counter-receptor for CD72. | Additional information: Clone REA421 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Tarakhovsky, A. et al. (1995) A role for CD5 in TCR-mediated signal transduction and thymocyte selection. Science 269 (5223): 535–537. | Efanov, A. et al. (2010) CD5+CD23+ leukemic cell populations in TCL1 transgenic mice show significantly increased proliferation and Akt phosphorylation. Leukemia 24 (5): 970–975. | Lundy, S. K. et al. (2014) Characterization and activity of Fas ligand producing CD5+ B cells. Methods Mol. Biol. 1190: 81–102.
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CD5 Antibody, anti-mouse, APC-Vio® 770, REAfinity™, 30 µg in 200 µL
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