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CD49f Antibody, anti-human/mou

se, Vio® Bright FITC, REAfinity™, 100 tests in 200 µL
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  • 询价
  • Miltenyi Biotec已认证
  • 德国
  • 130-125-983
  • 2025年12月09日
  • Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
  • human cell line
  • human, mouse, non-human primate, other
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德国美天旎生物技术有限公司
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原：

      CD49f

    • 亚型：

      recombinant human IgG1

    • 形态：

      Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.

    • 保存条件：

      避光，4-8℃

    • 克隆性：

      REA518

    • 标记物：

      Vio Bright FITC

    • 适应物种：

      human, mouse, non-human primate, other

    • 保质期：

      24个月

    • 供应商：

      Miltenyi biotec

    • 宿主：

      human cell line

    • 应用范围：

      Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry

    • 浓度：

      1:50

    • 抗体英文名：

      CD49f Antibody, anti-human/mouse, REAfinity™

    • 抗体名：

      CD49f Antibody, anti-human/mouse, REAfinity™

    • 规格：

      100 tests in 200 µL

    Identification and enumeration of CD49f+ cells by flow cytometryClone REA518 recognizes the human and mouse CD49f antigen, a 120 kDa single-pass type I membrane protein, which is also known as integrin alpha-6 (ITGA6). Integrins are integral cell-surface proteins composed of an α chain and a β chain and are involved in cell adhesion as well as cell-surface mediated signaling. CD49f associates with integrin β1 chain (CD29) to form VLA-6 and with integrin β4 chain (CD104) to form the α6 β4 complex, which plays a critical structural role in the hemidesmosome and constitutes a receptor for laminin in epithelial cells. CD49f is furthermore expressed on T cells, monocytes, platelets, endothelial cells, trophoblasts of placenta, and spermatogonial stem cells. | Additional information: Clone REA518 displays negligible binding to Fc receptors.

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    图标文献和实验
    该产品被引用文献
    Hynes, R. O. (2002) Integrins: bidirectional, allosteric signaling machines. Cell 110 (6): 673–687. | Aumailley, M. et al. (1990) Antibody to integrin α 6 subunit specifically inhibits cell-binding to laminin fragment 8. Exp. Cell Res. 188 (1): 55–60. | Hemler, M. E. et al. (1988) Multiple very late antigen (VLA) heterodimers on platelets. Evidence for distinct VLA-2, VLA-5 (fibronectin receptor), and VLA-6 structures. J. Biol. Chem. 263: 7660–7665. | Carter, W. G. et al. (1990) Distinct functions for integrins α 3 β 1 in focal adhesions and α 6 β 4/bullous pemphigoid antigen in a new stable anchoring contact (SAC) of keratinocytes: relation to hemidesmosomes. J. Cell Biol. 111: 3141–3154.
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    • Clinical Chemistry and Other Laboratory Tests on Mouse Plasma or Serum

      .    Haller, F., Prehn, C., and Adamski, J. 2010. Quantification of steroids in human and mouse plasma using online solid phase extraction coupled to liquid chromatography tandem mass spectrometry. Nat. Protoc. 10

    • secondary antibody review -- data from 99 publications

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    CD49f Antibody, anti-human/mouse, Vio® Bright FITC, REAfinity™, 100 tests in 200 µL
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