- 询价
- Miltenyi Biotec
- 德国
- 130-105-367
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD49c
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA360
- 标记物：
PE-Vio 770
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:11
- 抗体英文名：
CD49c Antibody, anti-human, REAfinity™
- 抗体名：
CD49c Antibody, anti-human, REAfinity™
- 规格：
100 tests in 1 mL
Identification and enumeration of CD49c+ cells by flow cytometryClone REA360 recognizes the human CD49c antigen, a single-pass type I membrane protein also known as integrin α-3 (ITGA3) or VLA-3α. CD49c forms a heterodimer with integrin β1 (α3β1, CD49c/CD29, VLA-3) and plays a role in neural migration and corticogenesis, acted upon by such factors as netrin-1 and reelin. It is expressed by many types of adhesion cells, such as endothelial cells, epithelial cells, and dermal fibroblasts. Weak expression has been reported on leukocytes. CD49c/CD29 plays a role in cell-cell and cell-matrix adhesion through binding fibronectin, laminin, collagen, epiligrin, thrombospondin, and CSPG4. | Additional information: Clone REA360 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Carter, W. G. et al. (1991) Epiligrin, a new cell adhesion ligand for integrin alpha 3 beta 1 in epithelial basement membranes. Cell 65 (4): 599–610. | Takada, Y. et al. (1991) Molecular cloning and expression of the cDNA for alpha 3 subunit of human alpha 3 beta 1 (VLA-3), an integrin receptor for fibronectin, laminin, and collagen. J. Cell Biol. 115 (1): 257–266. | de Melker, A. A. et al. (1997) The A and B variants of the alpha 3 integrin subunit: tissue distribution and functional characterization. Lab. Invest. 76 (4): 547–563.
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CD49c Antibody, anti-human, PE-Vio® 770, REAfinity™, 100 tests in 1 mL
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