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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD43
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA503
- 标记物:
APC
- 适应物种:
rat
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:10
- 抗体英文名:
CD43 Antibody, anti-rat, REAfinity™
- 抗体名:
CD43 Antibody, anti-rat, REAfinity™
- 规格:
30 µg in 1 mL
Identification and enumeration of CD43+ cells by flow cytometryClone REA503 recognizes the rat CD43 cell surface antigen, also known as leukosialin or sialophorin, which is a 371 amino acid heavily glycosylated single-pass type 1 transmebrane glycoprotein. | CD43 is expressed by most hematopoietic cells including peripheral T cells, NK cells, granulocytes, monocytes, thymocytes, platelets, plasma cells, activated B cells, and hemotopoietic progenitor cells. Leukosialin is involved in the costimulation of cell activation and survival as well as in cell-cell adhesion and anti-adhesion, and plays a role in inducement the apoptosis of T cells and hematopoietic progenitor cells. | Additional information: Clone REA503 displays negligible binding to Fc receptors. | |
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文献和实验该产品被引用文献
van den Berg, T. K. et al. (2001) Cutting Edge: CD43 functions as a T cell counterreceptor for the macrophage adhesion receptor Sialoadhesin (Siglec-1). J Immunol 166 (6): 3637–3640. | Killeen, N. et al. (1987) The sequence of rat leukosialin (W3/13 antigen) reveals a molecule with O-linked glycosylation of one third of its extracellular amino acids. EMBO J. 6 (13): 4029–4034. | Barclay, A. N. (1981) The localization of populations of lymphocytes defined by monoclonal antibodies in rat lymphoid tissues. Immunology 42 (4): 593–600.
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CD43 Antibody, anti-rat, APC, REAfinity™, 30 µg in 1 mL
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