- 询价
- Miltenyi Biotec
- 德国
- 130-121-423
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human, non-human primate
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD41a
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA386
- 标记物：
APC-Vio 770
- 适应物种：
human, non-human primate
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
CD41a Antibody, anti-human, REAfinity™
- 抗体名：
CD41a Antibody, anti-human, REAfinity™
- 规格：
30 tests in 60 µL
Identification and enumeration of CD41a+ cells by flow cytometryClone REA386 recognizes the human CD41a antigen, a calcium-dependent complex of CD41/CD61 (GPIIb/IIIa) expressed on normal platelets and megakaryocytes. The CD41/CD61 complex is a receptor for fibronectin, fibrinogen, von Willebrand factor, vitronectin, and thrombospondin and is required for platelet aggregation and clotting. Mutations of either CD41 or CD61 in humans causes Glanzmann’s thrombasthenia. Notably, CD41 is also the first blood-specific marker during in vitro differentiation of embryonic stem cells and is expressed on all hematopoietic stem and progenitor cells in the early embryo. However, CD41 expression is downregulated in midgestation embryos, and it is currently thought that CD41 expression on adult hematopoietic stem cells remains switched off throughout adult life. | Additional information: Clone REA386 displays negligible binding to Fc receptors.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验该产品被引用文献
Gekas, C. et al. (2013) CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age. Blood 121 (22): 4463–4472. | Poncz, M. et al. (1987) Structure of the platelet membrane glycoprotein IIb. Homology to the alpha subunits of the vitronectin and fibronectin membrane receptors. J. Biol. Chem. 262 (18): 8476–8482.
技术资料暂无技术资料 索取技术资料
文献支持
CD41a Antibody, anti-human, APC-Vio® 770, REAfinity™, 30 tests in 60 µL
询价
