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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD40
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA965
- 标记物:
Vio Bright B515
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
CD40 Antibody, anti-mouse, REAfinity™
- 抗体名:
CD40 Antibody, anti-mouse, REAfinity™
- 规格:
30 µg in 200 µL
Identification and enumeration of CD40+ cells by flow cytometryClone REA965 recognizes the mouse CD40 antigen, a 40–50 kDa glycoprotein and member of the tumor necrosis factor receptor (TNFR) family. CD40 is expressed on B lymphocytes, macrophages, and dendritic cells. It is an important costimulatory molecule for B cells as well as dendritic cells, monocytes, and other antigen-presenting cells (APCs). The interaction of CD40 on B cells with its ligand CD154 is involved in B cell activation and differentiation; engagement of CD40 on dendritic cells leads to maturation. | Additional information: Clone REA965 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Torres, R. M. et al. (1992) Differential increase of an alternatively polyadenylated mRNA species of murine CD40 upon B lymphocyte activation. J Immunol 148 (2): 620–626. | Tone, M. et al. (2001) Regulation of CD40 function by its isoforms generated through alternative splicing. Proc. Natl. Acad. Sci. U.S.A. 98 (4): 1751–1756.
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CD40 Antibody, anti-mouse, Vio® Bright B515, REAfinity™, 30 µg in 200 µL
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