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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD4
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA604
- 标记物:
APC
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
CD4 Antibody, anti-mouse, REAfinity™
- 抗体名:
CD4 Antibody, anti-mouse, REAfinity™
- 规格:
150 µg in 1 mL
Identification and enumeration of CD4+ cells by flow cytometryClone REA604 recognizes the mouse CD4 antigen, a cell surface glycoprotein, which is a member of the immunoglobulin superfamily. It is also known as L3T4 or Leu-3. In mice, CD4 is expressed on T helper cells, regulatory T cells, and at lower levels on subpopulations of NKT cells and dendritic cells. It is furthermore detected on most thymocytes (CD4+CD8+ and CD4+CD8– thymocytes). CD4 interacts with MHC class II molecules on the surface of antigen-presenting cells. It increases the avidity of the interaction between T cells and antigen-presenting or target cells. | Additional information: Clone REA604 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Tourvieille, B. et al. (1986) Isolation and sequence of L3T4 complementary DNA clones: expression in T cells and brain. Science 234 (4776): 610–614. | Bierer, B. E. et al. (1989) The biologic roles of CD2, CD4, and CD8 in T-cell activation. Annu. Rev. Immunol. 7: 579–599. | Parnes, J. R. et al. (1987) L3T4 and the immunoglobulin gene superfamily: new relationships between the immune system and the nervous system. Immunol. Rev. 100: 109–127.
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CD4 Antibody, anti-mouse, APC, REAfinity™, 150 µg in 1 mL
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