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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD38
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA616
- 标记物:
Biotin
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:10
- 抗体英文名:
CD38 Antibody, anti-mouse, REAfinity™
- 抗体名:
CD38 Antibody, anti-mouse, REAfinity™
- 规格:
30 µg in 1 mL
Identification and enumeration of CD38+ cells by flow cytometryClone REA616 recognizes the mouse CD38 antigen, a 42 kDa single-pass type II membrane protein, which is also known as ADP-ribosyl cyclase 1. CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis. In the mouse, CD38+ hematopoietic cells include B cells, subsets of T cells, monocytes, and macrophages. CD38 expression on these cells is modulated following activation and differentiation. In contrast to humans, CD38 expression is downregulated on mouse germinal center B cells and mouse mature plasma cells. | Additional information: Clone REA616 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Oliver, A. M. et al. (1997) Mouse CD38 is down-regulated on germinal center B cells and mature plasma cells. J Immunol 158 (3): 1108–1115. | Cockayne, D. A. et al. (1998) Mice deficient for the ecto-nicotinamide adenine dinucleotide glycohydrolase CD38 exhibit altered humoral immune responses. Blood 92 (4): 1324–1333. | Howard, M. et al. (1993) Formation and hydrolysis of cyclic ADP-ribose catalyzed by lymphocyte antigen CD38. Science 262 (5136): 1056–1059. | Bean, A. G. et al. (1995) CD38 expression on mouse T cells: CD38 defines functionally distinct subsets of alpha beta TCR+CD4-CD8- thymocytes. Int. Immunol. 7 (2): 213–221.
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CD38 Antibody, anti-mouse, Biotin, REAfinity™, 30 µg in 1 mL
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