- 询价
- Miltenyi Biotec
- 德国
- 130-109-263
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD371 (CLEC12A)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA594
- 标记物：
PE
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:10
- 抗体英文名：
CD371 (CLEC12A) Antibody, anti-mouse, REAfinity™
- 抗体名：
CD371 (CLEC12A) Antibody, anti-mouse, REAfinity™
- 规格：
30 µg in 1 mL
Identification and enumeration of CD371 (CLEC12A)+ cells by flow cytometryClone REA594 recognizes the mouse CD371 (CLEC12A) antigen, a 30 kDa type II transmembrane protein with extracellular C-type lectin domains. CD371 (CLEC12A) is a member of the C-type lectin/C-type lectin–like domain (CTL/CTLD) superfamily which have a common protein fold and plays a role in cell adhesion, cell-cell signaling, glycoprotein turnover, inflammation, and immune response.CD371 expression is primarily found on granulocytes and monocytes but also on CD8+ dendritic cells (DCs), plasmacytoid DCs, granulocytes, and B cells. It associates with the signaling phosphatases SHP-1 and SHP-2, but not with SHIP and is a negative regulator of granulocyte and monocyte function. | Additional information: Clone REA594 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Lahoud, M. H. et al. (2009) The C-type lectin Clec12A present on mouse and human dendritic cells can serve as a target for antigen delivery and enhancement of antibody responses. J Immunol 182 (12): 7587–7594. | Chen, C. H. et al. (2006) Dendritic-cell-associated C-type lectin 2 (DCAL-2) alters dendritic-cell maturation and cytokine production. Blood 107 (4): 1459–1467. | Marshall, A. S. et al. (2004) Identification and characterization of a novel human myeloid inhibitory C-type lectin-like receptor (MICL) that is predominantly expressed on granulocytes and monocytes. J. Biol. Chem. 279 (15): 14792–14802.
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CD371 (CLEC12A) Antibody, anti-mouse, PE, REAfinity™, 30 µg in 1 mL
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