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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD370 (CLEC9A)
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA976
- 标记物:
APC-Vio 770
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, Mass cytometry
- 浓度:
1:50
- 抗体英文名:
CD370 (CLEC9A) Antibody, anti-human, REAfinity™
- 抗体名:
CD370 (CLEC9A) Antibody, anti-human, REAfinity™
- 规格:
100 tests in 200 µL
Identification and enumeration of CD370 (CLEC9A)+ cells by flow cytometryClone REA976 recognizes the human CD370 antigen, also known as C-type lectin domain family 9 member A (CLEC9A). CD370 is a type II transmembrane glycoprotein member of 241 amino acids with a predicted molecular mass of ~30 kDa. It is also known as DNGR-1 and is expressed on BDCA-3+ myeloid dendritic cells from peripheral blood and lymphoid tissues. CD370 acts as a receptor for necrotic cells and plays an important role in cross-presentation. | Additional information: Clone REA976 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Poulin, L. F. et al. (2010) Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8 alpha+ dendritic cells. J. Exp. Med. 207 (6): 1261–1271. | Sancho, D. et al. (2008) Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin. J. Clin. Invest. 118 (6): 2098–2110. | Sancho, D. et al. (2009) Identification of a dendritic cell receptor that couples sensing of necrosis to immunity. Nature 458 (7240): 899–903.
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CD370 (CLEC9A) Antibody, anti-human, APC-Vio® 770, REAfinity™, 100 tests in 200 µL
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