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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD34
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA383
- 标记物:
FITC
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:50
- 抗体英文名:
CD34 Antibody, anti-mouse, REAfinity™
- 抗体名:
CD34 Antibody, anti-mouse, REAfinity™
- 规格:
30 µg in 200 µL
Identification and enumeration of CD34+ cells by flow cytometryClone REA383 recognizes the mouse CD34 antigen, a highly glycosylated single-pass type I membrane protein also known as mucosialin. CD34 is highly expressed in hematopoietic progenitor cell lines, as well as on endothelial cells, brain, and testis. It is a adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. CD34 acts as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. | Additional information: Clone REA383 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Suda, J. et al. (1992) Two types of murine CD34 mRNA generated by alternative splicing. Blood 79 (9): 2288–2295. | Brown, J. et al. (1991) The gene encoding the stem cell antigen, CD34, is conserved in mouse and expressed in haemopoietic progenitor cell lines, brain, and embryonic fibroblasts. Int. Immunol. 3 (2): 175–184. | Nakauchi, H. et al. (1999) Further characterization of CD34-low/negative mouse hematopoietic stem cells. Ann. N. Y. Acad. Sci. 872: 57–66.
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CD34 Antibody, anti-mouse, FITC, REAfinity™, 30 µg in 200 µL
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