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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD336 (NKp44)
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA1163
- 标记物:
Biotin
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, Mass cytometry
- 浓度:
1:50
- 抗体英文名:
CD336 (NKp44) Antibody, anti-human, REAfinity™
- 抗体名:
CD336 (NKp44) Antibody, anti-human, REAfinity™
- 规格:
100 tests in 200 µL
Identification and enumeration of CD336 (NKp44)+ cells by flow cytometryClone REA1163 recognizes the human CD336 antigen, also known as NKp44. CD336 is a member of the natural cytotoxicity receptor (NCR) family which trigger cytotoxicity in natural killer (NK) cells. CD336 is directly involved in target cell recognition and lysis and is only expressed by activated NK cells, e.g., NK cells cultured in the presence of interleukin 2 (IL-2). Freshly isolated, resting NK cells do not express CD336. | Additional information: Clone REA1163 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Vitale, M. et al. (1998) NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complex-restricted tumor cell lysis. J. Exp. Med. 187: 2065–2072. | Sivori, S. et al. (2000) 2B4 functions as a co-receptor in human NK cell activation. Eur. J. Immunol. 30: 787–793. | Moretta, A. et al. (2001) Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis. Annu. Rev. Immunol. 19: 197–223. | Chaput, N. et al. (2013) Phase I clinical trial combining imatinib mesylate and IL-2: HLA-DR+ NK cell levels correlate with disease outcome. Oncoimmunology 2 (2): e23080.
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CD336 (NKp44) Antibody, anti-human, Biotin, REAfinity™, 100 tests in 200 µL
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