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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD334 (FGFR4)
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA1243
- 标记物:
PE-Vio 770
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:50
- 抗体英文名:
CD334 (FGFR4) Antibody, anti-human, REAfinity™
- 抗体名:
CD334 (FGFR4) Antibody, anti-human, REAfinity™
- 规格:
100 tests in 200 µL
Identification and enumeration of CD334 (FGFR4)+ cells by flow cytometryClone REA1243 recognizes the human CD334 (FGFR4) antigen, known as Fibroblast growth factor receptor 4, which is a member of the fibroblast growth factor receptor family. This cell surface tyrosine kinase is a high affinity receptor for both acidic and basic fibroblast growth factor. The binding of CD334 with the acidic fibroblast growth factors FGF2, FGF6, and FGF8, FGF19 and GFG1 induces mitogenesis and differentiation. CD334 is expressed in adrenal, lung, kidney, liver, pancreas, intestine, striated muscle and spleen tissues of human fetuses. A soluble-form splice variant of FGFR 4 was identified in human gastrointestinal epithelial cells and cancer cells. | Additional information: Clone REA1243 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Partanan, J. et al. (1991) FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern. EMBO J. 10 (6): 1347–1354. | Takaishi, S. et al. (2000) Identification of a novel alternative splicing of human FGF receptor 4: soluble-form splice variant expressed in human gastrointestinal epithelial cells. Biochem. Biophys. Res. Commun. 267 (2): 658–662. | Ron, D. et al. (1993) Fibroblast growth factor receptor 4 is a high affinity receptor for both acidic and basic fibroblast growth factor but not for keratinocyte growth factor. J. Biol. Chem. 268 (8): 5388–5394.
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CD334 (FGFR4) Antibody, anti-human, PE-Vio® 770, REAfinity™, 100 tests in 200 µL
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