- 询价
- Miltenyi Biotec
- 德国
- 130-107-647
- 2025年12月09日
- Flow cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD329 (Siglec-9)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA492
- 标记物：
Biotin
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:11
- 抗体英文名：
CD329 (Siglec-9) Antibody, anti-human, REAfinity™
- 抗体名：
CD329 (Siglec-9) Antibody, anti-human, REAfinity™
- 规格：
30 tests in 300 µL
Identification and enumeration of CD329 (Siglec-9)+ cells by flow cytometryClone REA492 recognizes the human CD329 antigen, a single-pass type I membrane protein also known as sialic acid-binding Ig-like lectin 9 (Siglec-9). Siglecs are characterized by an amino-terminal V-set immunoglobulin domain that binds to sialic acid residues, followed by a variable number of C2-set immunoglobulin-like domains. CD329 is expressed quite broadly among human blood leukocytes, being found on monocytes, neutrophils, B cells, NK cells, and minor subsets of T cells. Ligation of CD329 induced apoptosis in adult neutrophils in a caspase-dependent manner; in contrast, its activation under inflammatory conditions resulted in a caspase-independent autophagic type of cell death. These disparate actions implicate a unique role for CD329 in modulating cell survival under inflammatory and basal conditions. | Additional information: Clone REA492 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Tanida, S. et al. (2013) Binding of the sialic acid-binding lectin, Siglec-9, to the membrane mucin, MUC1, induces recruitment of β-catenin and subsequent cell growth. J. Biol. Chem. 288 (44): 31842–31852. | Zhang, J. Q. et al. (2000) Siglec-9, a novel sialic acid binding member of the immunoglobulin superfamily expressed broadly on human blood leukocytes. J. Biol. Chem. 275 (29): 22121–22126. | Foussias, G. et al. (2000) Identification and molecular characterization of a novel member of the siglec family (SIGLEC9). Genomics 67 (2): 171–178.
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CD329 (Siglec-9) Antibody, anti-human, Biotin, REAfinity™, 30 tests in 300 µL
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