- 询价
- Miltenyi Biotec
- 德国
- 130-135-543
- 2025年12月09日
- Flow cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD337 (NKp30)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA823
- 标记物：
PE-Vio 670
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 抗体英文名：
CD337 (NKp30) Antibody, anti-human, REAfinity™
- 抗体名：
CD337 (NKp30) Antibody, anti-human, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of CD337 (NKp30)+ cells by flow cytometryClone REA823 recognizes the CD337 (NKp30) receptor, which is a 30 kDa type I membrane glycoprotein characterized by a single V-type Ig-like domain in the extracellular portion. CD337 is found almost exclusively on the surface of resting or activated natural killer (NK) cells and is a member of the natural cytotoxicity receptor (NCR) family which trigger cytotoxicity in NK cells. CD337 is directly involved in target cell recognition and lysis and is expressed by all resting or activated NK cells and by a small subset of T cells. Its expression density parallels that of CD336 (NKp44). It seems to be involved in killing of cells which are lysed independently from CD336 (NKp44) and CD335 (NKp46). | Additional information: Clone REA823 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Pende, D. et al. (1999) Identification and molecular characterization of Nkp30, a novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells. J. Exp. Med. 190: 1505–1516. | Sivori, S. et al. (2000) 2B4 functions as a co-receptor in human NK cell activation. Eur. J. Immunol. 30: 787–793. | Moretta, A. et al. (2001) Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis. Annu. Rev. Immunol. 19: 197–223. | Moretta, L. and Moretta, A. (2004) Unravelling natural killer function: Triggering and inhibitory human NK receptors. EMBO J. 23: 255–259.
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CD337 (NKp30) Antibody, anti-human, PE-Vio® 670, REAfinity™, 100 tests in 200 µL
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