- 询价
- Miltenyi Biotec
- 德国
- 130-102-750
- 2025年12月09日
- Flow cytometry
- human cell line
- rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD32
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA256
- 标记物：
APC
- 适应物种：
rat
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:10
- 抗体英文名：
CD32 Antibody, anti-rat, REAfinity™
- 抗体名：
CD32 Antibody, anti-rat, REAfinity™
- 规格：
30 µg in 1 mL
Identification and enumeration of CD32+ cells by flow cytometryClone REA256 recognizes the CD32 antigen, a 40 kDa polymorphic transmembrane glycoprotein also known as low affinity immunoglobulin gamma Fc region receptor II (FcγRII or FCRII). CD32 is a surface receptor protein and part of a large population of B cell co-receptors, which act to modulate signaling. Rat CD32 is expressed by B lymphocytes, myeloid cells, some lymphocytes in the thymic medulla, and cells which appear homologous to plasmacytoid dendritic cells. It mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to aggregated IgG and immune complexes and down-regulates antibody production in the presence of IgG. This feedback loops essentially lowers the production of IgG produced by B cells when there is a surplus in the body. | Additional information: Clone REA256 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Hubert, F. X. et al. (2004) Rat plasmacytoid dendritic cells are an abundant subset of MHC Class II+ CD4+CD11b–OX62– and type I IFN-producing cells that exhibit selective expression of Toll-like receptors 7 and 9 and strong responsiveness to CpG. J Immunol 172 (12): 7485–7494. | Lynch, R. G. et al. (2000) Regulatory roles for FcgammaRIII (CD16) and FcgammaRII (CD32) in the development of T- and B-lineage lymphoid cells. J Leukoc Biol 67: 279–284.
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CD32 Antibody, anti-rat, APC, REAfinity™, 30 µg in 1 mL
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