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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD309 (VEGFR-2)
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA1046
- 标记物:
PE-Vio 770
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
CD309 (VEGFR-2) Antibody, anti-human, REAfinity™
- 抗体名:
CD309 (VEGFR-2) Antibody, anti-human, REAfinity™
- 规格:
100 tests in 200 µL
Identification and enumeration of CD309 (VEGFR-2)+ cells by flow cytometryClone REA1046 recognizes the CD309 antigen, a transmembrane tyrosine kinase, also known as vascular endothelial growth factor receptor-2 (VEGFR-2) or kinase insert domain–containing receptor (KDR). CD309 is a high-affinity receptor for VEGF and plays a role in hematopoiesis. It is also involved in angiogenesis, both during embryogenesis and in the context of homeostatic or pathological events, e.g., vascularization of tumors. It has been identified on a subset of hematopoietic stem cells (HSCs), endothelial progenitor cells (EPCs), as well as on their common progenitor, the hemangioblast. CD309 expression is also found on mature endothelial cells (ECs). | Additional information: Clone REA1046 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Flamme, I. et al. (1995) Vascular endothelial growth factor (VEGF) and VEGF receptor 2 (flk-1) are expressed during vasculogenesis and vascular differentiation in the quail embryo. Dev. Biol. 169: 699–712. | Shalaby, F. et al. (1995) Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376: 62–66. | Auerbach, R. et al. (1996) Hematopoietic stem cells in the mouse embryonic yolk sac. Stem Cells 14: 269–280. | Eichmann, A. et al. (1997) Ligand-dependent development of the endothelial and hemopoietic lineages from embryonic mesodermal cells expressing vascular endothelial growth factor receptor 2. Proc. Natl. Acad. Sci. U.S.A. 94: 5141–5146.
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CD309 (VEGFR-2) Antibody, anti-human, PE-Vio® 770, REAfinity™, 100 tests in 200 µL
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