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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD307d (FcRL4)
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA890
- 标记物:
APC
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:50
- 抗体英文名:
CD307d (FcRL4) Antibody, anti-human, REAfinity™
- 抗体名:
CD307d (FcRL4) Antibody, anti-human, REAfinity™
- 规格:
30 tests in 60 µL
Identification and enumeration of CD307d (FcRL4)+ cells by flow cytometryClone REA890 recognizes the human CD307d antigen, a single-pass type I transmembrane protein also known as Fc receptor homolog 4 (FcRL4) or IRTA1. CD307d belongs to the Fc receptor homologue family, which members contain three potential immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their intracellular domain. CD307d is abundantly expressed on memory B cells and is able to inhibit the B cell receptor (BCR) signaling. | Additional information: Clone REA890 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Miller, I. et al. (2002) IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells. Blood 99 (8): 2662–2669. | Ehrhardt, G. R. et al. (2003) The inhibitory potential of Fc receptor homolog 4 on memory B cells. Proc. Natl. Acad. Sci. U.S.A. 100 (23): 13489–13494. | Ehrhardt, G. R. et al. (2005) Expression of the immunoregulatory molecule FcRH4 defines a distinctive tissue-based population of memory B cells. J. Exp. Med. 202 (6): 783–791.
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文献支持
CD307d (FcRL4) Antibody, anti-human, APC, REAfinity™, 30 tests in 60 µL
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