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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD301a (MGL1)
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA581
- 标记物:
APC
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:10
- 抗体英文名:
CD301a (MGL1) Antibody, anti-mouse, REAfinity™
- 抗体名:
CD301a (MGL1) Antibody, anti-mouse, REAfinity™
- 规格:
9 µg in 300 µL
Identification and enumeration of CD301a (MGL1)+ cells by flow cytometryClone REA581 recognizes the mouse CD301a antigen, a type II transmembrane glycoprotein also known as macrophage galactose-type C-type lectin-1 (MGL1). CD301 has two genes, CD301a and CD301b, which are highly homologous. In contrast to CD301b, that recognizes N-acetylgalactosamine and galactose, including the O-linked Tn antigen, TF antigen, and core 2, CD301a is highly specific for Lewis X and Lewis A structures. It has been suggested that MGL1 is involved in the clearance of apoptotic cells. CD301a is expressed in alternatively activated macrophages. | Additional information: Clone REA581 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Raes, G. et al. (2005) Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation. J Leukoc Biol 77 (3): 321–327. | Singh, S. K. et al. (2009) Characterization of murine MGL1 and MGL2 C-type lectins: distinct glycan specificities and tumor binding properties. Mol. Immunol. 46 (6): 1240–1249. | Yuita, H. et al. (2005) Retardation of removal of radiation-induced apoptotic cells in developing neural tubes in macrophage galactose-type C-type lectin-1-deficient mouse embryos. Glycobiology 15 (12): 1368–1375.
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CD301a (MGL1) Antibody, anti-mouse, APC, REAfinity™, 9 µg in 300 µL
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