- 询价
- Miltenyi Biotec
- 德国
- 130-110-288
- 2025年12月09日
- Flow cytometry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD301 (CLEC10A)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA687
- 标记物：
APC
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:10
- 抗体英文名：
CD301 (CLEC10A) Antibody, anti-mouse, REAfinity™
- 抗体名：
CD301 (CLEC10A) Antibody, anti-mouse, REAfinity™
- 规格：
30 µg in 1 mL
Identification and enumeration of CD301 (CLEC10A)+ cells by flow cytometryClone REA687 recognizes the mouse CD301 (CLEC10A) antigen, which is a 40 kDa type II transmembrane glycoprotein expressed by immature DCs and activated macrophages. Mouse CD301 has two homologue genes, CD301a (MGL1) and CD301b (MGL2). CD301 is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily which plays a role in cell adhesion, cell-cell signaling, glycoprotein turnover, inflammation, and immune response. CD301 binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. | Additional information: Clone REA687 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Denda-Nagai, K. et al. (2010) Distribution and function of macrophage galactose-type C-type lectin 2 (MGL2/CD301b): efficient uptake and presentation of glycosylated antigens by dendritic cells. J. Biol. Chem. 285 (25): 19193–19204. | Tsuiji, M. et al. (2002) Molecular cloning and characterization of a novel mouse macrophage C-type lectin, mMGL2, which has a distinct carbohydrate specificity from mMGL1. J. Biol. Chem. 277 (32): 28892–28901. | Singh, S. K. et al. (2009) Characterization of murine MGL1 and MGL2 C-type lectins: distinct glycan specificities and tumor binding properties. Mol. Immunol. 46 (6): 1240–1249.
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CD301 (CLEC10A) Antibody, anti-mouse, APC, REAfinity™, 30 µg in 1 mL
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