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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD300e (IREM-2)
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA1070
- 标记物:
APC-Vio 770
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, Mass cytometry
- 浓度:
1:50
- 抗体英文名:
CD300e (IREM-2) Antibody, anti-human, REAfinity™
- 抗体名:
CD300e (IREM-2) Antibody, anti-human, REAfinity™
- 规格:
30 tests in 60 µL
Identification and enumeration of CD300e (IREM-2)+ cells by flow cytometryClone REA1070 recognizes the human CD300e, also known as IREM-2, LMIR6, or CMRF35-A5. This 34 kDa activating receptor of the immunglobulin superfamily is expressed on mature myeloid dendritic cells and monocytes and is down-regulated on immature dendritic cells (DCs). CD300e interacts with DAP-12, which mediates acivating signals. It is reported that the alloreactive response of naive T cells is enhanced by IREM-2 activation of mDCs. | Additional information: Clone REA1070 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Aguilar, H. et al. (2004) Molecular characterization of a novel immune receptor restricted to the monocytic lineage. J Immunol 173: 6703–6711. | Brckalo, T. et al. (2010) Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells. Eur. J. Immunol. 40 (3): 722–732.
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CD300e (IREM-2) Antibody, anti-human, APC-Vio® 770, REAfinity™, 30 tests in 60 µL
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