文献支持
CD299 (L-SIGN) Antibody, anti-
human, Vio® Bright FITC, REAfinity™, 30 tests in 300 µL- 询价
- Miltenyi Biotec
- 德国
- 130-109-303
- 2025年12月09日
- Flow cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD299 (L-SIGN)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA587
- 标记物：
Vio Bright FITC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:11
- 抗体英文名：
CD299 (L-SIGN) Antibody, anti-human, REAfinity™
- 抗体名：
CD299 (L-SIGN) Antibody, anti-human, REAfinity™
- 规格：
30 tests in 300 µL
Identification and enumeration of CD299 (L-SIGN)+ cells by flow cytometryClone REA587 recognizes the human CD299 (L-SIGN) antigen, a type II integral membrane protein, also known as C-type lectin domain family 4 member M (CLEC4M) or liver/lymph node-specific ICAM-3-grabbing non-integrin. CD299 is expressed by sinusoidal endothelial cells in lymph nodes and is found in placental endothelium but not in macrophages. It is also expressed in type II alveolar cells and lung endothelial cells. CD299 has a high affinity for both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. | Additional information: Clone REA587 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Bashirova, A. A. et al. (2001) A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection. J. Exp. Med. 193 (6): 671–678. | Jeffers, S. A. et al. (2004) CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus. Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15748–15753. | Pöhlmann, S. et al. (2001) DC-SIGNR, a DC-SIGN homologue expressed in endothelial cells, binds to human and simian immunodeficiency viruses and activates infection in trans. Proc. Natl. Acad. Sci. U.S.A. 98 (5): 2670–2675.
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CD299 (L-SIGN) Antibody, anti-human, Vio® Bright FITC, REAfinity™, 30 tests in 300 µL
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