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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD28
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA206
- 标记物:
PE-Vio 770
- 适应物种:
rat
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:10
- 抗体英文名:
CD28 Antibody, anti-rat, REAfinity™
- 抗体名:
CD28 Antibody, anti-rat, REAfinity™
- 规格:
30 µg in 1 mL
Identification and enumeration of CD28+ cells by flow cytometryClone REA206 recognizes rat CD28, a 44 kDa glycoprotein also known as Tp44. CD28 is a homodimeric type I transmembrane protein of the Ig receptor superfamily, composed of disulfide-linked subunits. It is a costimulatory molecule which is expressed on most thymocytes, CD4+ and CD8+ T cells, and NK cells. Expression of CD28 is down-regulated at late stages of terminal effector T cell differentiation. Ligation of CD28 with CD80 (B7-1) and CD86 (B7-2) provides a costimulatory signal for T cell activation. | Additional information: Clone REA206 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Clark, G. J. et al. (1992) Identification of a cDNA encoding the rat CD28 homologue. Immunogenetics 35 (1): 54–57. | Guo, L. et al. (2003) Simultaneous blockade of co-stimulatory signals, CD28 and ICOS, induced a stable tolerance in rat heart transplantation. Transpl Immunol. 12 (1): 41–48.
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CD28 Antibody, anti-rat, PE-Vio® 770, REAfinity™, 30 µg in 1 mL
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