- 询价
- Miltenyi Biotec
- 德国
- 130-111-804
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD279 (PD1)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA802
- 标记物：
PerCP-Vio 700
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
CD279 (PD1) Antibody, anti-mouse, REAfinity™
- 抗体名：
CD279 (PD1) Antibody, anti-mouse, REAfinity™
- 规格：
150 µg in 1 mL
Identification and enumeration of CD279 (PD1)+ cells by flow cytometryClone REA802 recognizes the mouse CD279 antigen, also known as PD1. CD279 is a member of the Ig superfamily expressed mainly on activated T and B lymphocytes. Expression is induced on activated myeloid cells as well. CD279 is thought to be involved in lymphocyte clonal selection and plays a key role in peripheral tolerance and autoimmune disease in mice. The ligands of CD279, PDL1 (B7-H1) and PDL2 (B7-DC), belong to the B7 immunoglobulin superfamily. | Additional information: Clone REA802 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Iwai, Y. et al. (2002) Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc. Natl. Acad. Sci. U.S.A. 99: 12293–12297. | Salama, A. D. et al. (2003) Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis. J. Exp. Med. 198: 71–78. | Hirano, F. et al. (2005) Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunitiy. Cancer Res. 65: 1089–1096. | Tsushima, F. et al. (2007) Interaction between B7-H1 and PD-1 determines initiation and reversal of T cell anergy. Blood 110: 180–185.
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文献支持
CD279 (PD1) Antibody, anti-mouse, PerCP-Vio® 700, REAfinity™, 150 µg in 1 mL
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