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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD294 (CRTH2)
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA598
- 标记物:
PE-Vio 770
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, Mass cytometry
- 浓度:
1:50
- 抗体英文名:
CD294 (CRTH2) Antibody, anti-human, REAfinity™
- 抗体名:
CD294 (CRTH2) Antibody, anti-human, REAfinity™
- 规格:
100 tests in 200 µL
Identification and enumeration of CD294 (CRTH2)+ cells by flow cytometryClone REA598 recognizes the CD294 antigen, also known as chemoattractant receptor-homologous molecule expressed on Tʜ2 cells (CRTH2). CD294 is a seven-transmembrane G protein–coupled receptor for prostaglandin D2 involved in migration of leukocytes and is expressed on T helper type 2 (Tʜ2) cells, a subpopulation of CD4+ T cells, but not on Tʜ1 cells. The CD294 antigen is highly expressed on peripheral blood basophils and eosinophils. It is also present on a small population of CD8+ T cells and on a subpopulation of dendritic cells (DCs). | Additional information: Clone REA598 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Nagata, K. et al. (1999) Selective expression of a novel surface molecule by human Tʜ2 cells in vivo. J Immunol 162: 1278–1286. | Messi, M. et al. (2003) Memory and flexibility of cytokine gene expression as separable properties of human Tʜ1 and Tʜ2 lymphocytes. Nat Immunol 4: 78–86. | Nagata, K. et al. (1999) CRTH2, an orphan receptor of T-helper-2-cells, is expressed on basophils and eosinophils and responds to mast cell-derived factor(s). FEBS Lett. 459: 195–199.
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CD294 (CRTH2) Antibody, anti-human, PE-Vio® 770, REAfinity™, 100 tests in 200 µL
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