- 询价
- Miltenyi Biotec
- 德国
- 130-118-571
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD276
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA1094
- 标记物：
APC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
CD276 Antibody, anti-human, REAfinity™
- 抗体名：
CD276 Antibody, anti-human, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of CD276+ cells by flow cytometryClone REA1094 recognizes the human CD276 antigen, a type I transmembrane protein expressed at low levels in human liver, lung, bladder, testis, prostate, breast, placenta, lymphoid organs, and many human cancers. Surface expression can be induced on T cells, natural killer cells, and macrophages as well as on dendritic cells (DC) by interferon γ (IFN-γ) and on monocytes by granulocyte macrophage colony-stimulating factor (GM-CSF) and interleukin 4 (IL-4). CD276 has been shown to function as costimulatory molecule for T cell activation by inducing T cell proliferation and IFN-γ production. | Additional information: Clone REA1094 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Chapoval, A. I. et al. (2001) B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production. Nat Immunol 2 (3): 269–274. | Castriconi, R. et al. (2004) Identification of 4Ig-B7-H3 as a neuroblastoma-associated molecule that exerts a protective role from an NK cell-mediated lysis. Proc. Natl. Acad. Sci. U.S.A. 101 (34): 12640–12645. | Chen, Y. W. et al. (2008) The immunoregulatory protein human B7H3 is a tumor-associated antigen that regulates tumor cell migration and invasion. Curr. Cancer Drug Targets 8 (5): 404–413.
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CD276 Antibody, anti-human, APC, REAfinity™, 100 tests in 200 µL
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