- 询价
- Miltenyi Biotec
- 德国
- 130-116-769
- 2025年12月09日
- Flow cytometry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD273 (PD-L2)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA986
- 标记物：
APC-Vio 770
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 抗体英文名：
CD273 (PD-L2) Antibody, anti-mouse, REAfinity™
- 抗体名：
CD273 (PD-L2) Antibody, anti-mouse, REAfinity™
- 规格：
30 µg in 200 µL
Identification and enumeration of CD273 (PD-L2)+ cells by flow cytometryClone REA986 recognizes CD273, a member of the B7 family of protein ligands. CD273, along with another member of the B7 family (B7-H1) are ligands of T-cell receptor known as programmed death-1 (PD-1). Surface expression of B7-DC is restricted to dendritic cells (DCs) and activated or IFNγ-stimulated DCs and macrophages. CD273/PD-1 interaction is involved in inhibition of T-cell activation, however a co-stimulatory role of CD273, via interaction with receptor other then PD-1 is also reported. | Additional Information: Clone REA986 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Tseng, S. Y. et al. (2001) B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J. Exp. Med. 193: 839–846. | Wang, S. et al. (2003) Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction. J. Exp. Med. 197: 1083. | Greenwald, R. J. et al. (2005) The B7 family revisited. Annu. Rev. Immunol. 23: 515–548.
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CD273 (PD-L2) Antibody, anti-mouse, APC-Vio® 770, REAfinity™, 30 µg in 200 µL
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