- 询价
- Miltenyi Biotec
- 德国
- 130-112-601
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human, non-human primate, other
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD271 (LNGFR)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA844
- 标记物：
PE
- 适应物种：
human, non-human primate, other
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
CD271 (LNGFR) Antibody, anti-human, REAfinity™
- 抗体名：
CD271 (LNGFR) Antibody, anti-human, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of CD271 (LNGFR)+ cells by flow cytometryClone REA844 recognizes the human CD271 antigen, also known as low-affinity nerve growth factor receptor (LNGFR) or p75 neurotrophin receptor (NTR). CD271 belongs to the low-affinity neurotrophin receptors and the tumor necrosis factor receptor superfamily. Initially the human CD271 (LNGFR) was described to be expressed on cells of the central and peripheral nervous system and was suggested to be involved in the development, survival, and differentiation of cells. | Expression of CD271 (LNGFR) is found on mesenchymal stem/stromal cells (MSCs), follicular dendritic cells, mesenchymal cells involved in mesenchymal-epithelial interactions, autonomic and sensory neurons, oligodendrocytes, astrocytes, schwann cells, and neural crest stem cells. | Additional information: Clone REA844 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Caneva, L. et al. (1995) Immuno-electron microscopy characterization of human bone marrow stromal cells with anti-NGFR antibodies. Blood Cells Mol. Dis. 21: 73–85. | Quirici, N. et al. (2002) Isolation of bone marrow mesenchymal stem cells by anti-nerve growth factor receptor antibodies. Exp. Hematol. 30: 783–791. | Casaccia-Bonnefil, P. et al. (1996) Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75. Nature 383: 716–719. | DiStefano, P. S. and Johnson, E. M. Jr. (1988) Identification of a truncated form of the nerve growth factor receptor. Proc. Natl. Acad. Sci. U.S.A. 85: 270–274. | Huber, L. J. and Chao, M. V. (1995) Mesenchymal and neuronal cell expression of the p75 neurotrophin receptor gene occur by different mechanisms. Dev. Biol. 167: 227–238. | Chalazonitis, A. et al. (1998) Age-dependent differences in the effects of GDNF and NT-3 on the development of neurons and glia from neural crest-derived precursors immunoselected from the fetal rat gut: expression of GFRalpha-1 in vitro and in vivo. Dev. Biol. 204 (2): 385–406. | Jones, E. A. et al. (2002) Isolation and characterization of bone marrow multipotential mesenchymal progenitor cells. Arthritis Rheum 46: 3349–3360. | Kashiba, H. et al. (1995) Coexpression of trk family members and low-affinity neurotrophin receptors in rat dorsal root ganglion neurons. Brain Res. Mol. Brain Res. 30: 158–164. | Rudge, J. S. et al. (1994) Neurotrophic factor receptors and their signal transduction capabilities in rat astrocytes. Eur. J. Neurosci. 6: 693–705. | Thomson, T. M. et al. (1988) Expression of human nerve growth factor receptor on cells derived from all three germ layers. Exp. Cell Res. 174: 533–539. | Pezzati, P. et al. (1992) Expression of nerve growth factor receptor immunoreactivity on follicular dendritic cells from human mucosa associated lymphoid tissues. Immunology 76: 485–490. | Rozemuller, H. et al. (2010) Prospective isolation of mesenchymal stem cells from multiple mammalian species using cross-reacting anti-human monoclonal antibodies. Stem Cells Dev. 19: 1911–1921. | Vroemen, M. and Weidner, N. (2003) Purification of Schwann cells by selection of p75 low affinity nerve growth factor receptor expressing cells from adult peripheral nerve. J. Neurosci. Methods 124: 135–143.
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文献支持
CD271 (LNGFR) Antibody, anti-human, PE, REAfinity™, 100 tests in 200 µL
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