- 询价
- Miltenyi Biotec
- 德国
- 130-102-772
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD270 (HVEM)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA275
- 标记物：
APC
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:10
- 抗体英文名：
CD270 (HVEM) Antibody, anti-mouse, REAfinity™
- 抗体名：
CD270 (HVEM) Antibody, anti-mouse, REAfinity™
- 规格：
30 µg in 1 mL
Identification and enumeration of CD270 (HVEM)+ cells by flow cytometryClone REA275 recognizes the CD270 antigen, a type I transmembrane protein of the TNF-receptor superfamily which is also known as Herpes virus entry mediator (HVEM) or tumor necrosis factor receptor like 2 (TR2). CD270 is expressed in multiple tissues and cell lines and shows a constitutive and relatively high expression in peripheral blood T cells, B cells, monocytes, neutrophils and dendritic cells. Both human and mouse forms of CD270 can mediate entry of herpes simplex virus-1 and -2 (HSV-1 and HSV-2). CD270 transmits both activating and inhibitory signals; e.g interaction with receptors such as BTLA or CD160 attenuates TCR-mediated signaling, whereas interaction with receptor LIGHT allows co-stimulation of T and B cells. | Additional information: Clone REA275 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Hsu, H. et al. (1997) ATAR, a novel tumor necrosis factor receptor family member, signal through TRAF2 and TRAF5. J. Biol. Chem. 272: 13471–13474. | Kwon, B. S. et al. (1997) A newly identified member of the tumor necrosis factor receptor superfamily with a wide tissue distribution and involvement in lymphocyte activation. J. Biol. Chem. 272: 14272–14276. | Kim, W. K. et al. (2012) Absence of herpes virus entry mediator (HVEM) increases bone mass by attenuating receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesis. Endocrinology 153 (10): 4808–4817.
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CD270 (HVEM) Antibody, anti-mouse, APC, REAfinity™, 30 µg in 1 mL
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