- 询价
- Miltenyi Biotec
- 德国
- 130-101-595
- 2025年12月09日
- Flow cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD270 (HVEM)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA247
- 标记物：
FITC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:11
- 抗体英文名：
CD270 (HVEM) Antibody, anti-human, REAfinity™
- 抗体名：
CD270 (HVEM) Antibody, anti-human, REAfinity™
- 规格：
100 tests in 1 mL
Identification and enumeration of CD270 (HVEM)+ cells by flow cytometryClone REA247 recognizes CD270, which is also known as HVEM and derives its name based on the ability of types 1 and 2 herpesvirus gD to bind to it for entry into the cell. CD270 is a type 1 transmembrane protein with a predicted molecular weight of 30 kDa and is a member of the TNFR superfamily. CD270 transmits both activating and inhibitory signals for, e.g., interaction with receptors such as BTLA or CD160 attenuates TCR-mediated signaling, whereas interaction with receptor LIGHT allows co-stimulation of T and B cells. Expression of CD270 is widely distributed and is found on hematopoietic cells such as dendritic cells, Tregs, monocytes, neutrophils, NK cells, B cells, and T cells, as well as on non-hematopoietic cells. | Additional information: Clone REA247 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Ware, C. F. et al. (2009) Targeting the LIGHT-HVEM pathway. Adv. Exp. Med. Biol. 647: 146–155. | Pasero, C. et al. (2012) The HVEM network: new directions in targeting novel costimulatory/co-inhibitory molecules for cancer therapy. Curr. Opin. Pharmacol. 12 (4): 478–485.
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文献支持
CD270 (HVEM) Antibody, anti-human, FITC, REAfinity™, 100 tests in 1 mL
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