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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD273 (PD-L2)
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA985
- 标记物:
APC
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Mass cytometry
- 浓度:
1:50
- 抗体英文名:
CD273 (PD-L2) Antibody, anti-human, REAfinity™
- 抗体名:
CD273 (PD-L2) Antibody, anti-human, REAfinity™
- 规格:
30 tests in 60 µL
Identification and enumeration of CD273 (PD-L2)+ cells by flow cytometryClone REA985 recognizes the human CD273 antigen, also known as B7-DC or PD-L2. CD273 with an approximate molecular weight of 29 kDa is a type I transmembrane protein, belonging to the B7 family of protein ligands and to the Ig superfamily. CD273 is mainly expressed on dendritic cells (DCs) and activated macrophages. It has been shown to interact with programmed-death-receptor 1 (PD-1). A stimulatory as well as a inhibitory role of CD273 in T cell activation has been proposed. | Additional information: Clone REA985 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Tseng, S. Y. et al. (2001) B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J. Exp. Med. 193: 839–846. | Greenwald, R. J. et al. (2005) The B7 family revisited. Annu. Rev. Immunol. 23: 515–548. | Pfistershammer, K. et al. (2006) No evidence for dualism in function and receptors: PD-L2/B7-DC is an inhibitory regulator of human T cell activation. Eur. J. Immunol. 36 (5): 1104–1113.
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CD273 (PD-L2) Antibody, anti-human, APC, REAfinity™, 30 tests in 60 µL
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