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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD261
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA1234
- 标记物:
Vio Bright V423
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:50
- 抗体英文名:
CD261 Antibody, anti-human, REAfinity™
- 抗体名:
CD261 Antibody, anti-human, REAfinity™
- 规格:
100 tests in 200 µL
Identification and enumeration of CD261+ cells by flow cytometryClone REA1234 recognizes the human antigen CD261, which is also known as DR4 or as TRAIL-R1. CD261 belongs to the TNF receptor family and is a receptor for TNFSF10/ Trail. It promotes the activation of NF-kappa-B and induces TRAIL-mediated apoptosis. CD261 is expressed on spleen, peripheral blood leukocytes, small intestine and thymus, but also in K-562 erythroleukemia cells, MCF-7 breast carcinoma cells and activated T-cells. | Additional information: Clone REA1234 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Pan, G. et al. (1997) The receptor for the cytotoxic ligand TRAIL. Science 276 (5309): 111–113. | Chaudhary, P. M. et al. (1997) Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway. Immunity 7 (6): 821–830.
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CD261 Antibody, anti-human, Vio® Bright V423, REAfinity™, 100 tests in 200 µL
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