- 询价
- Miltenyi Biotec
- 德国
- 130-119-286
- 2025年12月09日
- Flow cytometry, Mass cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD253
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA1113
- 标记物：
PE-Vio 615
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, Mass cytometry
- 浓度：
1:50
- 抗体英文名：
CD253 Antibody, anti-human, REAfinity™
- 抗体名：
CD253 Antibody, anti-human, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of CD253+ cells by flow cytometryClone REA1113 recognizes the human CD253 cytokine, a type II transmembrane protein also known as TNF-related apoptosis inducing ligand (TRAIL) or tumor necrosis factor ligand superfamily member 10 (TNFSF10), which induces the process of cell death. CD253 is predominantly found in spleen, lung, and prostate. It binds to the death receptors DR4 (TRAIL-RI) and DR5 (TRAIL-RII). CD253 can be expressed on transformed and virus infected cells. It can also be expressed on activated lymphocytes. | Additional information: Clone REA1113 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Wiley, S. R. et al. (1995) Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 3 (6): 673–682. | Pitti, R. M. et al. (1996) Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J. Biol. Chem. 271 (22): 12687–12690. | Almasan, A. et al. (2003) Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy. Cytokine Growth Factor Rev. 14 (3-4): 337–348.
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CD253 Antibody, anti-human, PE-Vio® 615, REAfinity™, 100 tests in 200 µL
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