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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD253
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA1030
- 标记物:
Vio Bright B515
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:50
- 抗体英文名:
CD253 Antibody, anti-mouse, REAfinity™
- 抗体名:
CD253 Antibody, anti-mouse, REAfinity™
- 规格:
30 µg in 200 µL
Identification and enumeration of CD253+ cells by flow cytometryClone REA1030 recognizes the mouse CD253 antigen, a type 2 transmembrane protein also known as TNF-related apoptosis-inducing ligand (TRAIL), APO-2 ligand (APO-2L), or TNF ligand superfamily member 10 (TNFSF10). CD253 is expressed on a variety of cells of the innate and adaptive immune system, including natural killer (NK) cells. Often expression is induced or upregulated upon activation. CD253 can trigger apoptosis through trimerization of death receptor DR5 (TRAILR). | Additional information: Clone REA1030 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Wiley, S. R. et al. (1995) Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 3 (6): 673–682. | Hofmann, K. (1999) The modular nature of apoptotic signaling proteins. Cell. Mol. Life Sci. 55 (8-9): 1113–1128. | Locksley, R. M. et al. (2001) The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 104 (4): 487–501.
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CD253 Antibody, anti-mouse, Vio® Bright B515, REAfinity™, 30 µg in 200 µL
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