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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD25
- 亚型:
recombinant human IgG1
- 形态:
Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
- 保存条件:
避光,4-8℃
- 克隆性:
REA570
- 标记物:
pure
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Mass cytometry, 3D-Immunofluorescence, Immunofluorescence, Immunohistochemistry, Mass cytometry
- 抗体英文名:
CD25 Antibody, anti-human, REAfinity™
- 抗体名:
CD25 Antibody, anti-human, REAfinity™
- 规格:
100 µg in 100 µL
Identification and enumeration of CD25+ cells by mass cytometryClone REA570 recognizes the human CD25 glycoprotein, also known as the low-affinity interleukin-2 receptor alpha chain (IL-2Rα). It associates with IL-2 receptor β (CD122) and γ chains (CD132) to form a high affinity IL-2R complex. CD25 is expressed on activated T and B cells, on macrophages, and on a subset of non-activated CD4+ regulatory T cells. Clone REA570 recognizes epitope region A. | Additional information: Clone REA570 displays negligible binding to Fc receptors
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文献和实验该产品被引用文献
Lee, S. H. et al. (2012) Cutting edge: a novel mechanism bridging innate and adaptive immunity: IL-12 induction of CD25 to form high-affinity IL-2 receptors on NK cells. J Immunol 189 (6): 2712–2716. | Piccirillo, C. A. et al. (2006) Development and function of naturally occurring CD4+ CD25+ regulatory T cells. J Leukoc Biol 3: 458–470. | Goudy, K. et al. (2013) Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity. Clin. Immunol. 146 (3): 248–261.
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CD25 Antibody, anti-human, pure, REAfinity™, 100 µg in 100 µL
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