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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD233
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA368
- 标记物:
APC
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
CD233 Antibody, anti-human, REAfinity™
- 抗体名:
CD233 Antibody, anti-human, REAfinity™
- 规格:
100 tests in 200 µL
Identification and enumeration of CD233+ cells by flow cytometryClone REA368 recognizes the human CD233 antigen, a multi-pass membrane protein also known as anion exchange protein 1 (AE1) or solute carrier family 4 member 1 (SLC4A1). CD233 is a phylogenetically preserved transport protein responsible for mediating the electroneutral anion exchange of chloride for bicarbonate across a plasma membrane. It is the major integral membrane glycoprotein of the erythrocyte membrane and is required for the normal flexibility and stability of the erythrocyte membrane as well as for the normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. CD233 mediates the chloride-bicarbonate exchange in the kidney, and is required for the normal acidification of the urine. | Additional information: Clone REA368 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Rungaldier, S. et al. (2013) Stomatin interacts with GLUT1/SLC2A1, band 3/SLC4A1, and aquaporin-1 in human erythrocyte membrane domains. Biochim. Biophys. Acta 1828 (3): 956–966. | Barneaud-Rocca, D. et al. (2013) Structural model of the anion exchanger 1 (SLC4A1) and identification of transmembrane segments forming the transport site. J. Biol. Chem. 288 (37): 26372–26384. | Al-Samir, S. et al. (2013) Activity and distribution of intracellular carbonic anhydrase II and their effects on the transport activity of anion exchanger AE1/SLC4A1. J. Physiol. 591 (20): 4963–4982.
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CD233 Antibody, anti-human, APC, REAfinity™, 100 tests in 200 µL
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