- 询价
- Miltenyi Biotec
- 德国
- 130-115-706
- 2025年12月09日
- Flow cytometry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD218a (IL-18Rα)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA947
- 标记物：
PE-Vio 770
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 抗体英文名：
CD218a (IL-18Rα) Antibody, anti-mouse, REAfinity™
- 抗体名：
CD218a (IL-18Rα) Antibody, anti-mouse, REAfinity™
- 规格：
30 µg in 200 µL
Identification and enumeration of CD218a (IL-18Rα)+ cells by flow cytometryClone REA947 recognizes the mouse CD218a antigen, also known as interleukin-18 receptor alpha (IL-18Rα). CD218a, a member of the immunoglobulin superfamily, is a subunit of the heterodimeric receptor complex of alpha- and beta-chains for the pleiotropic proinflammatory IL-18 cytokine. IL-18 belongs to the IL-1 superfamily and is expressed by monocytes, macrophages, epithelial cells, and keratinocytes. CD218a (IL-18Rα) is found on Tʜ1 cells, subsets of NK cells, and granulocytes. IL-18 plays a role in induction of inflammatory mediators, regulation of the cytotoxic activity of NK and T cells, and differentiation and activation of Tʜ1 and Tʜ2 cells. | Additional information: Clone REA947 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Wu, C. et al. (2003) IL-18 receptor beta-induced changes in the presentation of IL-18 binding sites affect ligand binding and signal transduction. J Immunol 170 (11): 5571–5577. | Sergi, B. et al. (2004) Interleukin 18 receptor. J. Biol. Regul. Homeost. Agents 18 (1): 55–61. | Huang, H. Y. et al. (2010) Eutopic endometrial interleukin-18 system mRNA and protein expression at the level of endometrial-myometrial interface in adenomyosis patients. Fertil. Steril. 94 (1): 33–39.
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CD218a (IL-18Rα) Antibody, anti-mouse, PE-Vio® 770, REAfinity™, 30 µg in 200 µL
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