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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD228
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA717
- 标记物:
Vio Bright FITC
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:50
- 抗体英文名:
CD228 Antibody, anti-human, REAfinity™
- 抗体名:
CD228 Antibody, anti-human, REAfinity™
- 规格:
100 tests in 200 µL
Identification and enumeration of CD228+ cells by flow cytometryClone REA717 recognizes the human CD228 antigen, a cell-surface sialoglycoprotein also known as MFI2 or melanotransferrin. CD228 is mainly found in human melanomas, but also in liver, epithelium, and in certain fetal tissues. It plays a role in iron cellular uptake. CD228 is internalized before being recycled back to the cell membrane and is also able to bind zinc. | Additional information: Clone REA717 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Baker, E. N. et al. (1992) Human melanotransferrin (p97) has only one functional iron-binding site. FEBS Lett. 298 (2-3): 215–218. | Kennard, M. L. et al. (1995) A novel iron uptake mechanism mediated by GPI-anchored human p97. EMBO J. 14 (17): 4178–4186. | Suryo Rahmanto, Y. et al. (2007) The melanoma tumor antigen, melanotransferrin (p97): a 25-year hallmark--from iron metabolism to tumorigenesis. Oncogene 26 (42): 6113–6124.
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CD228 Antibody, anti-human, Vio® Bright FITC, REAfinity™, 100 tests in 200 µL
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