- 询价
- Miltenyi Biotec
- 德国
- 130-118-710
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD218 (IL-18Rα)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA1095
- 标记物：
APC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
CD218 (IL-18Rα) Antibody, anti-human, REAfinity™
- 抗体名：
CD218 (IL-18Rα) Antibody, anti-human, REAfinity™
- 规格：
30 tests in 60 µL
Identification and enumeration of CD218 (IL-18Rα)+ cells by flow cytometryClone REA1095 recognizes the CD218 antigen, which is also known as interleukin-18 receptor alpha (IL-18Rα) chain. IL-18 receptor is an heterodimeric receptor complex, and composed of the IL-18Rα chain and the IL-1 receptor accessory protein-like (IL-1RacPL) or IL-18Rβ chain. CD218 represents the ligand-binding chain, whereas IL-18Rβ is suggested to assist in the formation of a high affinity complex and mediates intracellular signals. IL-18R is expressed on a variety of cells including macrophages, neutrophils, natural killer (NK) cells, endothelial, and smooth muscle cells and an upregulated expression is observed on naive T cells, T helper cell type 1 (Tʜ1) cells, and B cells, in the presence IL-12. | Additional information: Clone REA1095 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Nakamura, S. et al. (2000) Expression and responsiveness of human interleukin-18 receptor (IL-18R) on hematopoietic cell lines. Leukemia 14 (6): 1052–1059. | Kim, S. H. et al. (2001) Functional reconstitution and regulation of IL-18 activity by the IL-18Rβ chain. J Immunol 166: 148–154.
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CD218 (IL-18Rα) Antibody, anti-human, APC, REAfinity™, 30 tests in 60 µL
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