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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD200
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA532
- 标记物:
APC-Vio 770
- 适应物种:
rat
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:10
- 抗体英文名:
CD200 Antibody, anti-rat, REAfinity™
- 抗体名:
CD200 Antibody, anti-rat, REAfinity™
- 规格:
9 µg in 300 µL
Identification and enumeration of CD200+ cells by flow cytometryClone REA532 recognizes the rat CD200 antigen, which is a transmembrane glycoprotein containing two extracellular immunoglobulin domains and lacks intracellular signaling motifs or docking sites for adapter signaling molecules. CD200, also known as MRC OX-2 antigen, is expressed on a variety of tissues, including the nervous system, activated T cells, B cells, dendritic cells in lymphatic follicles, cells of glomeruli and ovarian degenerating follicles, and vascular endothelium. It is also distributed at the epithelium-derived tissues such as the thymus, retinas, and hair follicles. CD200 interacts with CD200R, an immunoglobulin superfamily inhibitory receptor expressed primarily on myeloid/monocyte lineage cells, and has a suppressive effect on T cell–mediated immune response. | Additional information: Clone REA532 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Clark, M. J. et al. (1985) MRC OX-2 antigen: a lymphoid/neuronal membrane glycoprotein with a structure like a single immunoglobulin light chain. EMBO J. 4 (1): 113–118. | Ya-Fen, J. S. et al. (2010) Distribution and expression of CD200 in the rat respiratory system under normal and endotoxin-induced pathological conditions. J. Anat. 216 (3): 407–416. | Barclay, A. N. et al. (1986) Neuronal/lymphoid membrane glycoprotein MRC OX-2 is a member of the immunoglobulin superfamily with a light-chain-like structure. Biochem. Soc. Symp. 51: 149–157.
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CD200 Antibody, anti-rat, APC-Vio® 770, REAfinity™, 9 µg in 300 µL
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