CD1d Antibody, anti-human, APC

Identification and enumeration of CD1d+ cells by flow cytometryClone REA1114 recognizes the human CD1d antigen, a member of the CD1 family of MHC class I like glycoproteins involved in presenting lipid-based antigens to T cells. CD1d-restricted repertoire of T cells include NKT cells expressing invariant chain T cell receptors (TCRs), T cells with diverse TCRs and naïve like T cells with intermediate expression levels of the transcription factor PLZF. Expression of CD1d is found on the surface of many cells, including hepatocytes and professional antigen-presenting cells (APCs), including splenic dendritic cells (DCs), macrophages and B cells, intestinal epithelial cells, foreskin keratinocytes, penile urethral epithelial cells and hepatocytes. | Additional information: Clone REA1114 displays negligible binding to Fc receptors.