- 询价
- Miltenyi Biotec
- 德国
- 130-126-166
- 2025年12月09日
- Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human
企业认证
相关产品推荐更多 >
CD161 Antibody, anti-human, PE, REAfinity™, 100 tests in 200 µL
询价
CD11c Antibody, anti-human, PE, REAdye_lease™, 200 µL
询价
FcεRIα Antibody, anti-human, PE, REAfinity™, 100 tests in 200 µL
询价CD69 Antibody, anti-mouse, APC, 30 µg in 200 µL
询价CD1d Antibody, anti-human, PE-Vio® 670, REAfinity™, 30 tests in 60 µL
询价
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD20 Cytoplasmic
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA543
- 标记物：
PE
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
CD20 Cytoplasmic Antibody, anti-human, REAfinity™
- 抗体名：
CD20 Cytoplasmic Antibody, anti-human, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of CD20 Cytoplasmic+ cells by flow cytometryClone REA543 recognizes the cytoplasmic domain of the human CD20 antigen, a non-glycosylated transmembrane protein of 33–37 kDa that is expressed on B lineage cells from the pre–B cell stage to the B cell lymphoblast stage. The antigen is further expressed on most malignant B cells. CD20 is not found on early B cell progenitors or plasma cells. Oligomers of CD20 form a Ca 2)+ channel and might function in the regulation of local responses during B cell activation. In vitro effects of CD20-specific antibodies on resting B cells indicate that CD20 is able to transduce an extracellular signal affecting the G0/G1 cell cycle transition. Studies have demonstrated that CD20-initiated intracellular signals involve tyrosine kinase activation and that CD20 is tightly associated with both serine and tyrosine kinases. | Additional information: Clone REA543 displays negligible binding to Fc receptors. | |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验该产品被引用文献
Einfeld, D. A. et al. (1988) Molecular cloning of the human B cell CD20 receptor predicts a hydrophobic protein with multiple transmembrane domains. EMBO J. 7 (3): 711–717. | Deans, J. P. et al. (1995) Association of 75/80-kDa phosphoproteins and the tyrosine kinases Lyn, Fyn, and Lck with the B cell molecule CD20. Evidence against involvement of the cytoplasmic regions of CD20. J. Biol. Chem. 270 (38): 22632–22638. | Vaughan, A. T. et al. (2015) Activatory and inhibitory Fcγ receptors augment rituximab-mediated internalization of CD20 independent of signaling via the cytoplasmic domain. J. Biol. Chem. 290 (9): 5424–5437.
技术资料暂无技术资料 索取技术资料
文献支持
CD20 Cytoplasmic Antibody, anti-human, PE, REAfinity™, 100 tests in 200 µL
询价
